Two-step ATP-driven opening of cohesin head
Abstract The cohesin ring is a protein complex composed of four core subunits: Smc1A, Smc3, Rad21 and Stag1/2. It is involved in chromosome segregation, DNA repair, chromatin organization and transcription regulation. Opening of the ring occurs at the “head” structure, formed of the ATPase domains o...
Guardado en:
Autores principales: | Íñigo Marcos-Alcalde, Jesús I. Mendieta-Moreno, Beatriz Puisac, María Concepción Gil-Rodríguez, María Hernández-Marcos, Diego Soler-Polo, Feliciano J. Ramos, José Ortega, Juan Pié, Jesús Mendieta, Paulino Gómez-Puertas |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/9d8b866162dc4999b46b4c8eaf6a54fb |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Things are not always what they seem: From Cornelia de Lange to KBG phenotype in a girl with genetic variants in NIPBL and ANKRD11
por: Ana Latorre‐Pellicer, et al.
Publicado: (2021) -
Disruption of NIPBL/Scc2 in Cornelia de Lange Syndrome provokes cohesin genome-wide redistribution with an impact in the transcriptome
por: Patricia Garcia, et al.
Publicado: (2021) -
Structure of the cohesin loader Scc2
por: William C. H. Chao, et al.
Publicado: (2017) -
Age-related decrease of meiotic cohesins in human oocytes.
por: Makiko Tsutsumi, et al.
Publicado: (2014) -
A nucleotide-controlled conformational switch modulates the activity of eukaryotic IMP dehydrogenases
por: Rubén M. Buey, et al.
Publicado: (2017)