Impact of Long-Term Erythromycin Therapy on the Oropharyngeal Microbiome and Resistance Gene Reservoir in Non-Cystic Fibrosis Bronchiectasis

Impact of Long-Term Erythromycin Therapy on the Oropharyngeal Microbiome and Resistance Gene Reservoir in Non-Cystic Fibrosis Bronchiectasis

ABSTRACT Long-term macrolide therapy reduces rates of pulmonary exacerbation in bronchiectasis. However, little is known about the potential for macrolide therapy to alter the composition and function of the oropharyngeal commensal microbiota or to increase the carriage of transmissible antimicrobia...

Full description

Saved in:
Bibliographic Details
Main Authors: Jocelyn M. Choo, Guy C. J. Abell, Rachel Thomson, Lucy Morgan, Grant Waterer, David L. Gordon, Steven L. Taylor, Lex E. X. Leong, Steve L. Wesselingh, Lucy D. Burr, Geraint B. Rogers
Format: article
Language:EN
Published: American Society for Microbiology 2018
Subjects:
antibiotic resistance
bronchiectasis
macrolide therapy
oropharyngeal microbiome
Microbiology
QR1-502
Online Access:https://doaj.org/article/9dccb828593f4ef89e2c94eed49f9713
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/9dccb828593f4ef89e2c94eed49f9713

Similar Items