Crossing the blood-brain-barrier with nanoligand drug carriers self-assembled from a phage display peptide

Bacteriophages can bind targets with only a few copies of a display peptide while most nanoparticles with thousands achieve poor binding. Here the authors form hierarchical arrangements of phage peptides to delivery siRNA across the blood brain barrier.

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Detalles Bibliográficos
Autores principales: Lin-Ping Wu, Davoud Ahmadvand, Junan Su, Arnaldur Hall, Xiaolong Tan, Z. Shadi Farhangrazi, S. Moein Moghimi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/9def93cd838b4e7488bbdf9487ba930d
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