Crossing the blood-brain-barrier with nanoligand drug carriers self-assembled from a phage display peptide

Bacteriophages can bind targets with only a few copies of a display peptide while most nanoparticles with thousands achieve poor binding. Here the authors form hierarchical arrangements of phage peptides to delivery siRNA across the blood brain barrier.

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Autores principales: Lin-Ping Wu, Davoud Ahmadvand, Junan Su, Arnaldur Hall, Xiaolong Tan, Z. Shadi Farhangrazi, S. Moein Moghimi
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Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/9def93cd838b4e7488bbdf9487ba930d
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spelling oai:doaj.org-article:9def93cd838b4e7488bbdf9487ba930d2021-12-02T14:40:19ZCrossing the blood-brain-barrier with nanoligand drug carriers self-assembled from a phage display peptide10.1038/s41467-019-12554-22041-1723https://doaj.org/article/9def93cd838b4e7488bbdf9487ba930d2019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12554-2https://doaj.org/toc/2041-1723Bacteriophages can bind targets with only a few copies of a display peptide while most nanoparticles with thousands achieve poor binding. Here the authors form hierarchical arrangements of phage peptides to delivery siRNA across the blood brain barrier.Lin-Ping WuDavoud AhmadvandJunan SuArnaldur HallXiaolong TanZ. Shadi FarhangraziS. Moein MoghimiNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Lin-Ping Wu
Davoud Ahmadvand
Junan Su
Arnaldur Hall
Xiaolong Tan
Z. Shadi Farhangrazi
S. Moein Moghimi
Crossing the blood-brain-barrier with nanoligand drug carriers self-assembled from a phage display peptide
description Bacteriophages can bind targets with only a few copies of a display peptide while most nanoparticles with thousands achieve poor binding. Here the authors form hierarchical arrangements of phage peptides to delivery siRNA across the blood brain barrier.
format article
author Lin-Ping Wu
Davoud Ahmadvand
Junan Su
Arnaldur Hall
Xiaolong Tan
Z. Shadi Farhangrazi
S. Moein Moghimi
author_facet Lin-Ping Wu
Davoud Ahmadvand
Junan Su
Arnaldur Hall
Xiaolong Tan
Z. Shadi Farhangrazi
S. Moein Moghimi
author_sort Lin-Ping Wu
title Crossing the blood-brain-barrier with nanoligand drug carriers self-assembled from a phage display peptide
title_short Crossing the blood-brain-barrier with nanoligand drug carriers self-assembled from a phage display peptide
title_full Crossing the blood-brain-barrier with nanoligand drug carriers self-assembled from a phage display peptide
title_fullStr Crossing the blood-brain-barrier with nanoligand drug carriers self-assembled from a phage display peptide
title_full_unstemmed Crossing the blood-brain-barrier with nanoligand drug carriers self-assembled from a phage display peptide
title_sort crossing the blood-brain-barrier with nanoligand drug carriers self-assembled from a phage display peptide
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/9def93cd838b4e7488bbdf9487ba930d
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