Silencing early viral replication in macrophages and dendritic cells effectively suppresses flavivirus encephalitis.
West Nile (WN) and St. Louis encephalitis (SLE) viruses can cause fatal neurological infection and currently there is neither a specific treatment nor an approved vaccine for these infections. In our earlier studies, we have reported that siRNAs can be developed as broad-spectrum antivirals for the...
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Auteurs principaux: | Chunting Ye, Sojan Abraham, Haoquan Wu, Premlata Shankar, N Manjunath |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2011
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Accès en ligne: | https://doaj.org/article/9e408482614e4fdf9cc1f803e1ad1616 |
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