Activation of Prp28 ATPase by phosphorylated Npl3 at a critical step of spliceosome remodeling

Yeast helicase Prp28 promotes the first step of spliceosome remodeling. By placing a photoactivatable unnatural amino acid in Prp28, the authors capture Prp28 in action revealing its dynamic interactions and cofactor Npl3.

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Autores principales:	Fu-Lung Yeh, Shang-Lin Chang, Golam Rizvee Ahmed, Hsin-I Liu, Luh Tung, Chung-Shu Yeh, Leah Stands Lanier, Corina Maeder, Che-Min Lin, Shu-Chun Tsai, Wan-Yi Hsiao, Wei-Hau Chang, Tien-Hsien Chang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/9e81c7d52d55433ab0c6e27d3c001065
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spelling	oai:doaj.org-article:9e81c7d52d55433ab0c6e27d3c0010652021-12-02T15:00:50ZActivation of Prp28 ATPase by phosphorylated Npl3 at a critical step of spliceosome remodeling10.1038/s41467-021-23459-42041-1723https://doaj.org/article/9e81c7d52d55433ab0c6e27d3c0010652021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23459-4https://doaj.org/toc/2041-1723Yeast helicase Prp28 promotes the first step of spliceosome remodeling. By placing a photoactivatable unnatural amino acid in Prp28, the authors capture Prp28 in action revealing its dynamic interactions and cofactor Npl3.Fu-Lung YehShang-Lin ChangGolam Rizvee AhmedHsin-I LiuLuh TungChung-Shu YehLeah Stands LanierCorina MaederChe-Min LinShu-Chun TsaiWan-Yi HsiaoWei-Hau ChangTien-Hsien ChangNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Fu-Lung Yeh Shang-Lin Chang Golam Rizvee Ahmed Hsin-I Liu Luh Tung Chung-Shu Yeh Leah Stands Lanier Corina Maeder Che-Min Lin Shu-Chun Tsai Wan-Yi Hsiao Wei-Hau Chang Tien-Hsien Chang Activation of Prp28 ATPase by phosphorylated Npl3 at a critical step of spliceosome remodeling
description	Yeast helicase Prp28 promotes the first step of spliceosome remodeling. By placing a photoactivatable unnatural amino acid in Prp28, the authors capture Prp28 in action revealing its dynamic interactions and cofactor Npl3.
format	article
author	Fu-Lung Yeh Shang-Lin Chang Golam Rizvee Ahmed Hsin-I Liu Luh Tung Chung-Shu Yeh Leah Stands Lanier Corina Maeder Che-Min Lin Shu-Chun Tsai Wan-Yi Hsiao Wei-Hau Chang Tien-Hsien Chang
author_facet	Fu-Lung Yeh Shang-Lin Chang Golam Rizvee Ahmed Hsin-I Liu Luh Tung Chung-Shu Yeh Leah Stands Lanier Corina Maeder Che-Min Lin Shu-Chun Tsai Wan-Yi Hsiao Wei-Hau Chang Tien-Hsien Chang
author_sort	Fu-Lung Yeh
title	Activation of Prp28 ATPase by phosphorylated Npl3 at a critical step of spliceosome remodeling
title_short	Activation of Prp28 ATPase by phosphorylated Npl3 at a critical step of spliceosome remodeling
title_full	Activation of Prp28 ATPase by phosphorylated Npl3 at a critical step of spliceosome remodeling
title_fullStr	Activation of Prp28 ATPase by phosphorylated Npl3 at a critical step of spliceosome remodeling
title_full_unstemmed	Activation of Prp28 ATPase by phosphorylated Npl3 at a critical step of spliceosome remodeling
title_sort	activation of prp28 atpase by phosphorylated npl3 at a critical step of spliceosome remodeling
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/9e81c7d52d55433ab0c6e27d3c001065
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Activation of Prp28 ATPase by phosphorylated Npl3 at a critical step of spliceosome remodeling

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