Dissecting transition cells from single-cell transcriptome data through multiscale stochastic dynamics
How to infer transient cells and cell-fate transitions from snap-shot single cell transcriptome dataset remains a major challenge. Here the authors present a multiscale approach to construct single-cell dynamical manifold, quantify cell stability, and compute transition trajectory and probability be...
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Auteurs principaux: | , , , |
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Format: | article |
Langue: | EN |
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Nature Portfolio
2021
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Accès en ligne: | https://doaj.org/article/9e98a51ef4064d648221ae7674fdbde4 |
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