Inducible arginase 1 deficiency in mice leads to hyperargininemia and altered amino acid metabolism.
Arginase deficiency is a rare autosomal recessive disorder resulting from a loss of the liver arginase isoform, arginase 1 (ARG1), which is the final step in the urea cycle for detoxifying ammonia. ARG1 deficiency leads to hyperargininemia, characterized by progressive neurological impairment, persi...
Enregistré dans:
| Auteurs principaux: | , , , , , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Public Library of Science (PLoS)
2013
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/9ea10de58c854949becce57c4833c47d |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|