The Capacity of <italic toggle="yes">Mycobacterium tuberculosis</italic> To Survive Iron Starvation Might Enable It To Persist in Iron-Deprived Microenvironments of Human Granulomas

ABSTRACT This study was conducted to investigate the role of iron deprivation in the persistence of Mycobacterium tuberculosis. We present evidence of iron restriction in human necrotic granulomas and demonstrate that under iron starvation M. tuberculosis persists, refractive to antibiotics and capa...

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Auteurs principaux: Krishna Kurthkoti, Hamel Amin, Mohlopheni J. Marakalala, Saleena Ghanny, Selvakumar Subbian, Alexandra Sakatos, Jonathan Livny, Sarah M. Fortune, Michael Berney, G. Marcela Rodriguez
Format: article
Langue:EN
Publié: American Society for Microbiology 2017
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Accès en ligne:https://doaj.org/article/9ea9094635ae48e2a25c39feefe73d81
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