The integrin-linked kinase-PINCH-parvin complex supports integrin αIIbβ3 activation.

Integrin-linked kinase (ILK) is an important signaling regulator that assembles into the heteroternary complex with adaptor proteins PINCH and parvin (termed the IPP complex). We recently reported that ILK is important for integrin activation in a Chinese hamster ovary (CHO) cell system. We previous...

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Autores principales: Shigenori Honda, Hiroko Shirotani-Ikejima, Seiji Tadokoro, Yoshiaki Tomiyama, Toshiyuki Miyata
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/9eee5e8aa5c046aa8afba6fb6384bfc9
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