Quantitative sensing and signalling of single-stranded DNA during the DNA damage response

DNA damage triggers checkpoint signalling mechanisms. Here the authors reveal differential phosphorylation of targets of the Mec1-Ddc2 checkpoint kinase by analyzing the effect of quantitatively different ssDNA signals.

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Autores principales: Susanne C. S. Bantele, Michael Lisby, Boris Pfander
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Q
Acceso en línea:https://doaj.org/article/9f130ee32d1b44878b33be6fd79ca709
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