Quantitative sensing and signalling of single-stranded DNA during the DNA damage response

DNA damage triggers checkpoint signalling mechanisms. Here the authors reveal differential phosphorylation of targets of the Mec1-Ddc2 checkpoint kinase by analyzing the effect of quantitatively different ssDNA signals.

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Autores principales: Susanne C. S. Bantele, Michael Lisby, Boris Pfander
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/9f130ee32d1b44878b33be6fd79ca709
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spelling oai:doaj.org-article:9f130ee32d1b44878b33be6fd79ca7092021-12-02T16:50:57ZQuantitative sensing and signalling of single-stranded DNA during the DNA damage response10.1038/s41467-019-08889-52041-1723https://doaj.org/article/9f130ee32d1b44878b33be6fd79ca7092019-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08889-5https://doaj.org/toc/2041-1723DNA damage triggers checkpoint signalling mechanisms. Here the authors reveal differential phosphorylation of targets of the Mec1-Ddc2 checkpoint kinase by analyzing the effect of quantitatively different ssDNA signals.Susanne C. S. BanteleMichael LisbyBoris PfanderNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Susanne C. S. Bantele
Michael Lisby
Boris Pfander
Quantitative sensing and signalling of single-stranded DNA during the DNA damage response
description DNA damage triggers checkpoint signalling mechanisms. Here the authors reveal differential phosphorylation of targets of the Mec1-Ddc2 checkpoint kinase by analyzing the effect of quantitatively different ssDNA signals.
format article
author Susanne C. S. Bantele
Michael Lisby
Boris Pfander
author_facet Susanne C. S. Bantele
Michael Lisby
Boris Pfander
author_sort Susanne C. S. Bantele
title Quantitative sensing and signalling of single-stranded DNA during the DNA damage response
title_short Quantitative sensing and signalling of single-stranded DNA during the DNA damage response
title_full Quantitative sensing and signalling of single-stranded DNA during the DNA damage response
title_fullStr Quantitative sensing and signalling of single-stranded DNA during the DNA damage response
title_full_unstemmed Quantitative sensing and signalling of single-stranded DNA during the DNA damage response
title_sort quantitative sensing and signalling of single-stranded dna during the dna damage response
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/9f130ee32d1b44878b33be6fd79ca709
work_keys_str_mv AT susannecsbantele quantitativesensingandsignallingofsinglestrandeddnaduringthednadamageresponse
AT michaellisby quantitativesensingandsignallingofsinglestrandeddnaduringthednadamageresponse
AT borispfander quantitativesensingandsignallingofsinglestrandeddnaduringthednadamageresponse
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