Quantitative sensing and signalling of single-stranded DNA during the DNA damage response
DNA damage triggers checkpoint signalling mechanisms. Here the authors reveal differential phosphorylation of targets of the Mec1-Ddc2 checkpoint kinase by analyzing the effect of quantitatively different ssDNA signals.
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Nature Portfolio
2019
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oai:doaj.org-article:9f130ee32d1b44878b33be6fd79ca7092021-12-02T16:50:57ZQuantitative sensing and signalling of single-stranded DNA during the DNA damage response10.1038/s41467-019-08889-52041-1723https://doaj.org/article/9f130ee32d1b44878b33be6fd79ca7092019-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08889-5https://doaj.org/toc/2041-1723DNA damage triggers checkpoint signalling mechanisms. Here the authors reveal differential phosphorylation of targets of the Mec1-Ddc2 checkpoint kinase by analyzing the effect of quantitatively different ssDNA signals.Susanne C. S. BanteleMichael LisbyBoris PfanderNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019) |
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DOAJ |
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EN |
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Science Q |
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Science Q Susanne C. S. Bantele Michael Lisby Boris Pfander Quantitative sensing and signalling of single-stranded DNA during the DNA damage response |
description |
DNA damage triggers checkpoint signalling mechanisms. Here the authors reveal differential phosphorylation of targets of the Mec1-Ddc2 checkpoint kinase by analyzing the effect of quantitatively different ssDNA signals. |
format |
article |
author |
Susanne C. S. Bantele Michael Lisby Boris Pfander |
author_facet |
Susanne C. S. Bantele Michael Lisby Boris Pfander |
author_sort |
Susanne C. S. Bantele |
title |
Quantitative sensing and signalling of single-stranded DNA during the DNA damage response |
title_short |
Quantitative sensing and signalling of single-stranded DNA during the DNA damage response |
title_full |
Quantitative sensing and signalling of single-stranded DNA during the DNA damage response |
title_fullStr |
Quantitative sensing and signalling of single-stranded DNA during the DNA damage response |
title_full_unstemmed |
Quantitative sensing and signalling of single-stranded DNA during the DNA damage response |
title_sort |
quantitative sensing and signalling of single-stranded dna during the dna damage response |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/9f130ee32d1b44878b33be6fd79ca709 |
work_keys_str_mv |
AT susannecsbantele quantitativesensingandsignallingofsinglestrandeddnaduringthednadamageresponse AT michaellisby quantitativesensingandsignallingofsinglestrandeddnaduringthednadamageresponse AT borispfander quantitativesensingandsignallingofsinglestrandeddnaduringthednadamageresponse |
_version_ |
1718382996930691072 |