Conformational analysis of isolated domains of Helicobacter pylori CagA.

The CagA protein of Helicobacter pylori is associated with increased virulence and gastric cancer risk. CagA is translocated into the host cell by a H. pylori type IV secretion system via mechanisms that are poorly understood. Translocated CagA interacts with numerous host factors, altering a variet...

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Autores principales: Amanda P Woon, Abolghasem Tohidpour, Hernan Alonso, Yumiko Saijo-Hamano, Terry Kwok, Anna Roujeinikova
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/9f14f6a09eed49eb84c834b795590d73
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