Tuning the dynamic range of bacterial promoters regulated by ligand-inducible transcription factors

For synthetic gene circuits to behave as designed, ligand-inducible promoters should display predictable ON/OFF characteristics. Here the authors design multi-input hybrid promoters to build transcriptional logic gates.

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Autores principales: Ye Chen, Joanne M. L. Ho, David L. Shis, Chinmaya Gupta, James Long, Daniel S. Wagner, William Ott, Krešimir Josić, Matthew R. Bennett
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/9f191ec1c7d248d3bde26396083e9a7b
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