Tuning the dynamic range of bacterial promoters regulated by ligand-inducible transcription factors

For synthetic gene circuits to behave as designed, ligand-inducible promoters should display predictable ON/OFF characteristics. Here the authors design multi-input hybrid promoters to build transcriptional logic gates.

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Autores principales: Ye Chen, Joanne M. L. Ho, David L. Shis, Chinmaya Gupta, James Long, Daniel S. Wagner, William Ott, Krešimir Josić, Matthew R. Bennett
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/9f191ec1c7d248d3bde26396083e9a7b
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spelling oai:doaj.org-article:9f191ec1c7d248d3bde26396083e9a7b2021-12-02T17:33:17ZTuning the dynamic range of bacterial promoters regulated by ligand-inducible transcription factors10.1038/s41467-017-02473-52041-1723https://doaj.org/article/9f191ec1c7d248d3bde26396083e9a7b2018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02473-5https://doaj.org/toc/2041-1723For synthetic gene circuits to behave as designed, ligand-inducible promoters should display predictable ON/OFF characteristics. Here the authors design multi-input hybrid promoters to build transcriptional logic gates.Ye ChenJoanne M. L. HoDavid L. ShisChinmaya GuptaJames LongDaniel S. WagnerWilliam OttKrešimir JosićMatthew R. BennettNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Ye Chen
Joanne M. L. Ho
David L. Shis
Chinmaya Gupta
James Long
Daniel S. Wagner
William Ott
Krešimir Josić
Matthew R. Bennett
Tuning the dynamic range of bacterial promoters regulated by ligand-inducible transcription factors
description For synthetic gene circuits to behave as designed, ligand-inducible promoters should display predictable ON/OFF characteristics. Here the authors design multi-input hybrid promoters to build transcriptional logic gates.
format article
author Ye Chen
Joanne M. L. Ho
David L. Shis
Chinmaya Gupta
James Long
Daniel S. Wagner
William Ott
Krešimir Josić
Matthew R. Bennett
author_facet Ye Chen
Joanne M. L. Ho
David L. Shis
Chinmaya Gupta
James Long
Daniel S. Wagner
William Ott
Krešimir Josić
Matthew R. Bennett
author_sort Ye Chen
title Tuning the dynamic range of bacterial promoters regulated by ligand-inducible transcription factors
title_short Tuning the dynamic range of bacterial promoters regulated by ligand-inducible transcription factors
title_full Tuning the dynamic range of bacterial promoters regulated by ligand-inducible transcription factors
title_fullStr Tuning the dynamic range of bacterial promoters regulated by ligand-inducible transcription factors
title_full_unstemmed Tuning the dynamic range of bacterial promoters regulated by ligand-inducible transcription factors
title_sort tuning the dynamic range of bacterial promoters regulated by ligand-inducible transcription factors
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/9f191ec1c7d248d3bde26396083e9a7b
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