Comparative proteomic analysis highlights metabolic dysfunction in α-synucleinopathy

Abstract The synaptic protein α-synuclein is linked through genetics and neuropathology to the pathogenesis of Parkinson’s disease and related disorders. However, the mechanisms by which α-synuclein influences disease onset and progression are incompletely understood. To identify pathogenic pathways...

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Autores principales: Souvarish Sarkar, Michael A. Murphy, Eric B. Dammer, Abby L. Olsen, Srikant Rangaraju, Ernest Fraenkel, Mel B. Feany
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/9f38af5472714532a0498ae12dfcd774
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