Comparative proteomic analysis highlights metabolic dysfunction in α-synucleinopathy
Abstract The synaptic protein α-synuclein is linked through genetics and neuropathology to the pathogenesis of Parkinson’s disease and related disorders. However, the mechanisms by which α-synuclein influences disease onset and progression are incompletely understood. To identify pathogenic pathways...
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Autores principales: | Souvarish Sarkar, Michael A. Murphy, Eric B. Dammer, Abby L. Olsen, Srikant Rangaraju, Ernest Fraenkel, Mel B. Feany |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
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Materias: | |
Acceso en línea: | https://doaj.org/article/9f38af5472714532a0498ae12dfcd774 |
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