Comparative proteomic analysis highlights metabolic dysfunction in α-synucleinopathy

Abstract The synaptic protein α-synuclein is linked through genetics and neuropathology to the pathogenesis of Parkinson’s disease and related disorders. However, the mechanisms by which α-synuclein influences disease onset and progression are incompletely understood. To identify pathogenic pathways...

Full description

Saved in:
Bibliographic Details
Main Authors: Souvarish Sarkar, Michael A. Murphy, Eric B. Dammer, Abby L. Olsen, Srikant Rangaraju, Ernest Fraenkel, Mel B. Feany
Format: article
Language:EN
Published: Nature Portfolio 2020
Subjects:
Online Access:https://doaj.org/article/9f38af5472714532a0498ae12dfcd774
Tags: Add Tag
No Tags, Be the first to tag this record!