Multi-locus test conditional on confirmed effects leads to increased power in genome-wide association studies.
Complex diseases or phenotypes may involve multiple genetic variants and interactions between genetic, environmental and other factors. Current genome-wide association studies (GWAS) mostly used single-locus analysis and had identified genetic effects with multiple confirmations. Such confirmed sing...
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Autores principales: | , , , |
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Formato: | article |
Lenguaje: | EN |
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Public Library of Science (PLoS)
2010
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Acceso en línea: | https://doaj.org/article/9f42d6e9135f4ee39050aff23309320e |
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