Multi-locus test conditional on confirmed effects leads to increased power in genome-wide association studies.

Multi-locus test conditional on confirmed effects leads to increased power in genome-wide association studies.

Complex diseases or phenotypes may involve multiple genetic variants and interactions between genetic, environmental and other factors. Current genome-wide association studies (GWAS) mostly used single-locus analysis and had identified genetic effects with multiple confirmations. Such confirmed sing...

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Autores principales: Li Ma, Shizhong Han, Jing Yang, Yang Da
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/9f42d6e9135f4ee39050aff23309320e
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