Gene network disruptions and neurogenesis defects in the adult Ts1Cje mouse model of Down syndrome.

Gene network disruptions and neurogenesis defects in the adult Ts1Cje mouse model of Down syndrome.

<h4>Background</h4>Down syndrome (DS) individuals suffer mental retardation with further cognitive decline and early onset Alzheimer's disease.<h4>Methodology/principal findings</h4>To understand how trisomy 21 causes these neurological abnormalities we investigated chan...

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Bibliographic Details
Main Authors: Chelsee A Hewitt, King-Hwa Ling, Tobias D Merson, Ken M Simpson, Matthew E Ritchie, Sarah L King, Melanie A Pritchard, Gordon K Smyth, Tim Thomas, Hamish S Scott, Anne K Voss
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2010
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/9f51062a00a048609ce9234d5876a4cf
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https://doaj.org/article/9f51062a00a048609ce9234d5876a4cf

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