Intestinal microbiome adjusts the innate immune setpoint during colonization through negative regulation of MyD88

It remains unclear how microbial sensing during early-life colonization results in immune homeostasis rather than acute inflammation. Here the authors show that zebrafish larvae colonization suppresses intestinal MyD88, accounting for a considerable proportion of microbiota-induced alterations in im...

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Autores principales: Bjørn E. V. Koch, Shuxin Yang, Gerda Lamers, Jens Stougaard, Herman P. Spaink
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/9f5a5a4c19844be095c1293f273062d8
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