Colon adenocarcinoma-derived cells possessing stem cell function can be modulated using renin-angiotensin system inhibitors.

The cancer stem cell (CSC) concept proposes that cancer recurrence and metastasis are driven by CSCs. In this study, we investigated whether cells from colon adenocarcinoma (CA) with a CSC-like phenotype express renin-angiotensin system (RAS) components, and the effect of RAS inhibitors on CA-derive...

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Auteurs principaux: Matthew J Munro, Lifeng Peng, Susrutha K Wickremesekera, Swee T Tan
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2021
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R
Q
Accès en ligne:https://doaj.org/article/9f855c6e7f49498b8728b7c5a6dfbb3e
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