Blockade of high-mobility group box 1 attenuates intestinal mucosal barrier dysfunction in experimental acute pancreatitis

Abstract The release of inflammatory cytokines, that plays a dominant role in local pancreatic inflammation and systemic complications in severe acute pancreatitis (SAP). High-mobility group box 1 (HMGB1) is implicated in the mechanism of organ dysfunction and bacterial translocation in SAP. This cu...

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Bibliographic Details
Main Authors: Xia Chen, Hong-Xian Zhao, Chao Bai, Xiang-Yu Zhou
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
R
Q
Online Access:https://doaj.org/article/9f9a2ac66e3e499f994cd96e7fc0145f
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