Creation of a long-acting nanoformulated dolutegravir
Current ART for treatment of HIV-1 infection requires a strict daily regimen adherence. Herein, the authors report the manufacture and characterization of a nanoformulated dolutegravir prodrug with improved cell and tissue penetration, a remarkable apparent half-life and the potential for bimonthly...
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Auteurs principaux: | , , , , , , , , , , , , , , |
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Format: | article |
Langue: | EN |
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Nature Portfolio
2018
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Accès en ligne: | https://doaj.org/article/9fe938444e464eaea1e85845549ff241 |
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