Frequent GU wobble pairings reduce translation efficiency in Plasmodium falciparum
Abstract Plasmodium falciparum genome has 81% A+T content. This nucleotide bias leads to extreme codon usage bias and culminates in frequent insertion of asparagine homorepeats in the proteome. Using recodonized GFP sequences, we show that codons decoded via G:U wobble pairing are suboptimal codons...
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Autores principales: | , , , |
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Formato: | article |
Lenguaje: | EN |
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Nature Portfolio
2017
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Acceso en línea: | https://doaj.org/article/a00b8d1b6c5a4836ba5159d5faf03e89 |
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