Host-specific asymmetric accumulation of mutation types reveals that the origin of SARS-CoV-2 is consistent with a natural process
The capacity of RNA viruses to adapt to new hosts and rapidly escape the host immune system is largely attributable to de novo genetic diversity that emerges through mutations in RNA. Although the molecular spectrum of de novo mutations—the relative rates at which various base substitutions occur—ar...
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Main Authors: | Ke-Jia Shan, Changshuo Wei, Yu Wang, Qing Huan, Wenfeng Qian |
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Format: | article |
Language: | EN |
Published: |
Elsevier
2021
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Online Access: | https://doaj.org/article/a0297591f49e4f3aa2ba6d3b93d4901b |
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