The Matrikine Acetylated Proline-Glycine-Proline Couples Vascular Inflammation and Acute Cardiac Rejection

Abstract The extracellular matrix (ECM) is a dynamic, bioactive structure critical to organ development, structure and function. Excessive remodeling of the ECM is a hallmark of a variety of inflammatory conditions including vascular disease. Endothelin-1 (ET1) synthesis is understood to promote car...

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Auteurs principaux: Gregory A. Payne, Jindong Li, Xin Xu, Patricia Jackson, Hongwei Qin, David M. Pollock, J. Michael Wells, Suzanne Oparil, Massoud Leesar, Rakesh P. Patel, J. Edwin Blalock, Amit Gaggar
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Accès en ligne:https://doaj.org/article/a02a41bb53f14b3b8aaea863666146da
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