Methotrexate Alters the Expression of microRNA in Fibroblast-like Synovial Cells in Rheumatoid Arthritis

Methotrexate Alters the Expression of microRNA in Fibroblast-like Synovial Cells in Rheumatoid Arthritis

We aimed to investigate the effect of methotrexate (MTX) on microRNA modulation in rheumatoid arthritis fibroblast-like synovial cells (RA-FLS). RA-FLS were treated with MTX for 48 h. We then performed miRNA array analysis to investigate differentially expressed miRNAs. Transfection with miR-877-3p...

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Detalles Bibliográficos
Autores principales: Naoki Iwamoto, Kaori Furukawa, Yushiro Endo, Toshimasa Shimizu, Remi Sumiyoshi, Masataka Umeda, Tomohiro Koga, Shin-ya Kawashiri, Takashi Igawa, Kunihiro Ichinose, Mami Tamai, Tomoki Origuchi, Atsushi Kawakami
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
MTX
miR-877-3p
rheumatoid arthritis
fibroblast-like synovial cells
microRNA
Biology (General)
QH301-705.5
Chemistry
QD1-999
Acceso en línea:https://doaj.org/article/a033ad1617144b1a895f980fda346391
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https://doaj.org/article/a033ad1617144b1a895f980fda346391

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