Overcoming false-positive gene-category enrichment in the analysis of spatially resolved transcriptomic brain atlas data

Identifying enriched gene sets in transcriptomic data is routine analysis. Here, the authors show that conventional gene category enrichment analysis (GCEA) applied to brain-wide atlas data yields biased results and develop a flexible ensemble-based null model framework to enable appropriate inferen...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Ben D. Fulcher, Aurina Arnatkeviciute, Alex Fornito
Format: article
Langue:EN
Publié: Nature Portfolio 2021
Sujets:
Q
Accès en ligne:https://doaj.org/article/a043385931fd4415a4b3a9fa307ff145
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!