Ectosomes: a new mechanism for non-exosomal secretion of tau protein.

Ectosomes: a new mechanism for non-exosomal secretion of tau protein.

Tau is a microtubule-associated protein that aggregates in neurodegenerative disorders known as tauopathies. Recently, studies have suggested that Tau may be secreted and play a role in neural network signalling. However, once deregulated, secreted Tau may also participate in the spreading of Tau pa...

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Main Authors: Simon Dujardin, Séverine Bégard, Raphaëlle Caillierez, Cédrick Lachaud, Lucie Delattre, Sébastien Carrier, Anne Loyens, Marie-Christine Galas, Luc Bousset, Ronald Melki, Gwennaëlle Aurégan, Philippe Hantraye, Emmanuel Brouillet, Luc Buée, Morvane Colin
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2014
Subjects:
Medicine
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Science
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Online Access:https://doaj.org/article/a06625b69c34481face921efb5d48b51
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