Reciprocal interactions between tumour cell populations enhance growth and reduce radiation sensitivity in prostate cancer

Using co-culture experiments and mathematical modelling, Paczkowski et al discover that prostate cancer spheroids comprising mixed tumour cell populations display enhanced growth and reduced radiation sensitivity due to competitive and antagonistic interactions between cell populations. This interdi...

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Autores principales: Marcin Paczkowski, Warren W. Kretzschmar, Bostjan Markelc, Stanley K. Liu, Leoni A. Kunz-Schughart, Adrian L. Harris, Mike Partridge, Helen M. Byrne, Pavitra Kannan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/a08140e263164d63ab72ee83c273ffdf
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