Reciprocal interactions between tumour cell populations enhance growth and reduce radiation sensitivity in prostate cancer

Using co-culture experiments and mathematical modelling, Paczkowski et al discover that prostate cancer spheroids comprising mixed tumour cell populations display enhanced growth and reduced radiation sensitivity due to competitive and antagonistic interactions between cell populations. This interdi...

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Auteurs principaux: Marcin Paczkowski, Warren W. Kretzschmar, Bostjan Markelc, Stanley K. Liu, Leoni A. Kunz-Schughart, Adrian L. Harris, Mike Partridge, Helen M. Byrne, Pavitra Kannan
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/a08140e263164d63ab72ee83c273ffdf
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