Rad50 zinc hook functions as a constitutive dimerization module interchangeable with SMC hinge

Rad50 zinc hook functions as a constitutive dimerization module interchangeable with SMC hinge

The Mre11/Rad50 complex, which functions in genome surveillance, possesses antiparallel coiled-coil arms forming a ring-like structure similar to that of the SMC family proteins. Here the authors find that the Rad50 zinc hook functions similarly to the hinge of the SMC protein, and that the ring str...

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Bibliographic Details
Main Authors: Hisashi Tatebe, Chew Theng Lim, Hiroki Konno, Kazuhiro Shiozaki, Akira Shinohara, Takayuki Uchihashi, Asako Furukohri
Format: article
Language:EN
Published: Nature Portfolio 2020
Subjects:
Science
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Online Access:https://doaj.org/article/a0985c5563bd43b498daec3196d6c305
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https://doaj.org/article/a0985c5563bd43b498daec3196d6c305

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