Lipid Flippase Subunit Cdc50 Mediates Drug Resistance and Virulence in <named-content content-type="genus-species">Cryptococcus neoformans</named-content>

ABSTRACT Cryptococcus neoformans is a human fungal pathogen and a major cause of fungal meningitis in immunocompromised individuals. Treatment options for cryptococcosis are limited. Of the two major antifungal drug classes, azoles are active against C. neoformans but exert a fungistatic effect, nec...

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Autores principales: Wei Huang, Guojian Liao, Gregory M. Baker, Yina Wang, Richard Lau, Padmaja Paderu, David S. Perlin, Chaoyang Xue
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2016
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Acceso en línea:https://doaj.org/article/a0ad3fbd5af340e1af74a174f7794498
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