<italic toggle="yes">Orientia tsutsugamushi</italic> Nucleomodulin Ank13 Exploits the RaDAR Nuclear Import Pathway To Modulate Host Cell Transcription

ABSTRACT Orientia tsutsugamushi is the etiologic agent of scrub typhus, the deadliest of all diseases caused by obligate intracellular bacteria. Nucleomodulins, bacterial effectors that dysregulate eukaryotic transcription, are being increasingly recognized as key virulence factors. How they translo...

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Autores principales: Haley E. Adcox, Amanda L. Hatke, Shelby E. Andersen, Sarika Gupta, Nathan B. Otto, Mary M. Weber, Richard T. Marconi, Jason A. Carlyon
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2021
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Acceso en línea:https://doaj.org/article/a0c1200611c0432fa459491bfbd46f6a
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