A Novel Isogenic Human Cell-Based System for MEN1 Syndrome Generated by CRISPR/Cas9 Genome Editing

Multiple endocrine neoplasia type 1 (MEN1) is a rare tumor syndrome that manifests differently among various patients. Despite the mutations in the <i>MEN1</i> gene that commonly predispose tumor development, there are no obvious phenotype–genotype correlations. The existing animal and i...

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Autores principales: Natalia Klementieva, Daria Goliusova, Julia Krupinova, Vladislav Yanvarev, Alexandra Panova, Natalia Mokrysheva, Sergey L. Kiselev
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/a116548ab2ac42498babf5e1ff263192
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