A Novel Isogenic Human Cell-Based System for MEN1 Syndrome Generated by CRISPR/Cas9 Genome Editing
Multiple endocrine neoplasia type 1 (MEN1) is a rare tumor syndrome that manifests differently among various patients. Despite the mutations in the <i>MEN1</i> gene that commonly predispose tumor development, there are no obvious phenotype–genotype correlations. The existing animal and i...
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Autores principales: | Natalia Klementieva, Daria Goliusova, Julia Krupinova, Vladislav Yanvarev, Alexandra Panova, Natalia Mokrysheva, Sergey L. Kiselev |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
MDPI AG
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/a116548ab2ac42498babf5e1ff263192 |
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