Permutation-based identification of important biomarkers for complex diseases via machine learning models

Study of human disease remains challenging due to convoluted disease etiologies and complex molecular mechanisms at genetic, genomic, and proteomic levels. Here, the authors propose a computationally efficient Permutation-based Feature Importance Test to assist interpretation and selection of indivi...

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Autores principales: Xinlei Mi, Baiming Zou, Fei Zou, Jianhua Hu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/a14b8c9fa4db459da160a337cbf281f4
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