Regulation of PXR Function by Coactivator and Corepressor Proteins: Ligand Binding Is Just the Beginning
The pregnane X receptor (PXR, <i>NR1I2</i>) is a nuclear receptor which exerts its regulatory function by heterodimerization with the retinoid-X-receptor α (RXRα, <i>NR2B1</i>) and binding to the promoter and enhancer regions of diverse target genes. PXR is involved in the re...
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| Main Authors: | , , , |
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| Format: | article |
| Language: | EN |
| Published: |
MDPI AG
2021
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| Subjects: | |
| Online Access: | https://doaj.org/article/a1554bc0021e43bca23c40e3b7c676fd |
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