Validation of drug-like inhibitors against Mycobacterium tuberculosis L-aspartate α-decarboxylase using nuclear magnetic resonance (1H NMR).
The catalytic activity of L-aspartate α-decarboxylase (ADC) is essential for the growth of several micro-organisms, including Mycobacterium tuberculosis (Mtb), and has triggered efforts for the development of pharmaceutically active compounds against tuberculosis. The present study is a continuation...
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Auteurs principaux: | , , , |
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Format: | article |
Langue: | EN |
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Public Library of Science (PLoS)
2012
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Accès en ligne: | https://doaj.org/article/a179f203babc4c89b292f030b11b9f82 |
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