Influence of cytochrome P450 2D6 polymorphism on hippocampal white matter and treatment response in schizophrenia

Abstract Cytochrome P450 2D6 (CYP2D6) is expressed at high levels in the brain and plays a considerable role in the biotransformation and neurotransmission of dopamine. This raises the question of whether CYP2D6 variations and its impact on the brain can confer susceptibility to schizophrenia. We in...

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Auteurs principaux: Wonsuk Shin, Minji Bang, Anhye Kim, Doo-Yeoun Cho, Sang-Hyuk Lee
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/a182e146ab9149d396ce0dc94cd46434
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