Protospacer-Adjacent Motif Specificity during <named-content content-type="genus-species">Clostridioides difficile</named-content> Type I-B CRISPR-Cas Interference and Adaptation

Protospacer-Adjacent Motif Specificity during <named-content content-type="genus-species">Clostridioides difficile</named-content> Type I-B CRISPR-Cas Interference and Adaptation

ABSTRACT CRISPR (clustered regularly interspaced short palindromic repeats)-Cas (CRISPR-associated) systems provide prokaryotes with efficient protection against foreign nucleic acid invaders. We have recently demonstrated the defensive interference function of a CRISPR-Cas system from Clostridioide...

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Bibliographic Details
Main Authors: Anna Maikova, Pierre Boudry, Anna Shiriaeva, Aleksandra Vasileva, Anaïs Boutserin, Sofia Medvedeva, Ekaterina Semenova, Konstantin Severinov, Olga Soutourina
Format: article
Language:EN
Published: American Society for Microbiology 2021
Subjects:
CRISPR-Cas interference
CRISPR-Cas adaptation
Clostridium difficile
PAM
type I-B CRISPR-Cas
enteropathogen
Microbiology
QR1-502
Online Access:https://doaj.org/article/a1a07cf6296041e9ad107cf56f8087f0
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https://doaj.org/article/a1a07cf6296041e9ad107cf56f8087f0

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