Promoter-proximal pausing mediated by the exon junction complex regulates splicing

The exon junction complex (EJC) has been identified as functioning as a post-transcriptional gene regulator. Here the authors reveal that the complex also plays a part in the regulation of transcription by regulating the release of Pol II pausing into transcription elongation.

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Autores principales: Junaid Akhtar, Nastasja Kreim, Federico Marini, Giriram Mohana, Daniel Brüne, Harald Binder, Jean-Yves Roignant
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/a1b644d0069147debd628820b07cf1c2
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