Promoter-proximal pausing mediated by the exon junction complex regulates splicing
The exon junction complex (EJC) has been identified as functioning as a post-transcriptional gene regulator. Here the authors reveal that the complex also plays a part in the regulation of transcription by regulating the release of Pol II pausing into transcription elongation.
Guardado en:
Autores principales: | Junaid Akhtar, Nastasja Kreim, Federico Marini, Giriram Mohana, Daniel Brüne, Harald Binder, Jean-Yves Roignant |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
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Materias: | |
Acceso en línea: | https://doaj.org/article/a1b644d0069147debd628820b07cf1c2 |
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