Promoter-proximal pausing mediated by the exon junction complex regulates splicing

The exon junction complex (EJC) has been identified as functioning as a post-transcriptional gene regulator. Here the authors reveal that the complex also plays a part in the regulation of transcription by regulating the release of Pol II pausing into transcription elongation.

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Junaid Akhtar, Nastasja Kreim, Federico Marini, Giriram Mohana, Daniel Brüne, Harald Binder, Jean-Yves Roignant
Format: article
Langue:EN
Publié: Nature Portfolio 2019
Sujets:
Q
Accès en ligne:https://doaj.org/article/a1b644d0069147debd628820b07cf1c2
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!