Transcriptomic Profiling of Human Pluripotent Stem Cell-derived Retinal Pigment Epithelium over Time

Transcriptomic Profiling of Human Pluripotent Stem Cell-derived Retinal Pigment Epithelium over Time

Human pluripotent stem cell (hPSC)-derived progenies are immature versions of cells, presenting a potential limitation to the accurate modelling of diseases associated with maturity or age. Hence, it is important to characterise how closely cells used in culture resemble their native counterparts. I...

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Autores principales: Grace E. Lidgerwood, Anne Senabouth, Casey J.A. Smith-Anttila, Vikkitharan Gnanasambandapillai, Dominik C. Kaczorowski, Daniela Amann-Zalcenstein, Erica L. Fletcher, Shalin H. Naik, Alex W. Hewitt, Joseph E. Powell, Alice Pébay
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
Materias:
Human embryonic stem cell
Human pluripotent stem cell
Retinal pigment epithelium
Single-cell RNA sequencing
Ageing
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/a1b752ada11e4c119fcf167e7656b297
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https://doaj.org/article/a1b752ada11e4c119fcf167e7656b297

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