Small nucleoli are a cellular hallmark of longevity

Animal lifespan is plastic and is regulated by conserved signalling pathways. Here, Tikuet al.show that longevity-enhancing mutations or interventions are associated with reduced nucleolar size in worms, flies, mice and humans, and that nucleolar size can predict life-expectancy in individual worms.

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Detalles Bibliográficos
Autores principales: Varnesh Tiku, Chirag Jain, Yotam Raz, Shuhei Nakamura, Bree Heestand, Wei Liu, Martin Späth, H. Eka. D. Suchiman, Roman-Ulrich Müller, P. Eline Slagboom, Linda Partridge, Adam Antebi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/a1c21506b6f54e62bbf007f51e842a46
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