Effect of the consumption of chocolate enriched with tryptophan and resveratrol on biochemical markers and oxidative stress in a healthy population

Background: Chocolate is a product with high nutritional value, of sensory characteristics accepted and preferred by the consumer, in addition to beneficial to health. Based on the benefits attributed to cocoa components, investigations have shown that chocolate consumption has been involved in the...

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Autores principales:	Jennyfer FLÓREZ-MENDEZ, Jorge Yezid FLÓREZ, Elevina PÉREZ, Mary LARES
Formato:	article
Lenguaje:	EN
Publicado:	Universidad de Antioquia 2019
Materias:	Antioxidant cocoa chocolate flavonoids resveratrol. Food processing and manufacture TP368-456 Pharmaceutical industry HD9665-9675
Acceso en línea:	https://doaj.org/article/a1d689ceaf1f4a2b8106aa9521056735
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spelling	oai:doaj.org-article:a1d689ceaf1f4a2b8106aa95210567352021-12-02T19:37:00ZEffect of the consumption of chocolate enriched with tryptophan and resveratrol on biochemical markers and oxidative stress in a healthy population10.17533/udea.vitae.v26n1a020121-40042145-2660https://doaj.org/article/a1d689ceaf1f4a2b8106aa95210567352019-04-01T00:00:00Zhttps://revistas.udea.edu.co/index.php/vitae/article/view/335020https://doaj.org/toc/0121-4004https://doaj.org/toc/2145-2660 Background: Chocolate is a product with high nutritional value, of sensory characteristics accepted and preferred by the consumer, in addition to beneficial to health. Based on the benefits attributed to cocoa components, investigations have shown that chocolate consumption has been involved in the modulation of blood pressure protection, the lipid profile, the activation of platelets, and insulin sensitivity. Objective: Evaluate the effect of consuming a tablet of chocolate enriched with tryptophan present in the peanut and resveratrol contained in the peel flour and grape seed, on biochemical markers and oxidative stress in a healthy population. Methods: The study was conducted in 10 subjects aged between 20 and 40 years, who consumed daily for 21 days, a chocolate bar of 15 g enriched with tryptophan and resveratrol. Before starting the study and after 21 days, the participants were given weighty measures, waist, hip and blood pressure. As well as blood samples, where was analyzed: glycemia, creatinine, triglycerides, total cholesterol, HDL, LDL, VLDL, uric acid, insulin and markers of oxidative stress 8- isoprostane and catalase. The non-parametric statistical tests were applied Kruskal-Wallis for n=10, with a value of significance of 0.05. Results: A statistically significant decrease in insulin values and oxidative stress marker 8-isoprostane was stopped, whereas catalase values increased significantly. Conclusions: The consumption of chocolate enriched with tryptophan and resveratrol, does not alter the biochemical parameters of glycemia, creatinine, triglycerides, total cholesterol, HDL, LDL, VLDL and uric acid. But it significantly helps the decrease of insulin in blood and could have beneficial health effects related to the reduction of oxidative stress, after consuming 15 g of the chocolate during 21 days. Jennyfer FLÓREZ-MENDEZJorge Yezid FLÓREZElevina PÉREZMary LARESUniversidad de AntioquiaarticleAntioxidantcocoachocolateflavonoidsresveratrol.Food processing and manufactureTP368-456Pharmaceutical industryHD9665-9675ENVitae, Vol 26, Iss 1 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Antioxidant cocoa chocolate flavonoids resveratrol. Food processing and manufacture TP368-456 Pharmaceutical industry HD9665-9675
spellingShingle	Antioxidant cocoa chocolate flavonoids resveratrol. Food processing and manufacture TP368-456 Pharmaceutical industry HD9665-9675 Jennyfer FLÓREZ-MENDEZ Jorge Yezid FLÓREZ Elevina PÉREZ Mary LARES Effect of the consumption of chocolate enriched with tryptophan and resveratrol on biochemical markers and oxidative stress in a healthy population
description	Background: Chocolate is a product with high nutritional value, of sensory characteristics accepted and preferred by the consumer, in addition to beneficial to health. Based on the benefits attributed to cocoa components, investigations have shown that chocolate consumption has been involved in the modulation of blood pressure protection, the lipid profile, the activation of platelets, and insulin sensitivity. Objective: Evaluate the effect of consuming a tablet of chocolate enriched with tryptophan present in the peanut and resveratrol contained in the peel flour and grape seed, on biochemical markers and oxidative stress in a healthy population. Methods: The study was conducted in 10 subjects aged between 20 and 40 years, who consumed daily for 21 days, a chocolate bar of 15 g enriched with tryptophan and resveratrol. Before starting the study and after 21 days, the participants were given weighty measures, waist, hip and blood pressure. As well as blood samples, where was analyzed: glycemia, creatinine, triglycerides, total cholesterol, HDL, LDL, VLDL, uric acid, insulin and markers of oxidative stress 8- isoprostane and catalase. The non-parametric statistical tests were applied Kruskal-Wallis for n=10, with a value of significance of 0.05. Results: A statistically significant decrease in insulin values and oxidative stress marker 8-isoprostane was stopped, whereas catalase values increased significantly. Conclusions: The consumption of chocolate enriched with tryptophan and resveratrol, does not alter the biochemical parameters of glycemia, creatinine, triglycerides, total cholesterol, HDL, LDL, VLDL and uric acid. But it significantly helps the decrease of insulin in blood and could have beneficial health effects related to the reduction of oxidative stress, after consuming 15 g of the chocolate during 21 days.
format	article
author	Jennyfer FLÓREZ-MENDEZ Jorge Yezid FLÓREZ Elevina PÉREZ Mary LARES
author_facet	Jennyfer FLÓREZ-MENDEZ Jorge Yezid FLÓREZ Elevina PÉREZ Mary LARES
author_sort	Jennyfer FLÓREZ-MENDEZ
title	Effect of the consumption of chocolate enriched with tryptophan and resveratrol on biochemical markers and oxidative stress in a healthy population
title_short	Effect of the consumption of chocolate enriched with tryptophan and resveratrol on biochemical markers and oxidative stress in a healthy population
title_full	Effect of the consumption of chocolate enriched with tryptophan and resveratrol on biochemical markers and oxidative stress in a healthy population
title_fullStr	Effect of the consumption of chocolate enriched with tryptophan and resveratrol on biochemical markers and oxidative stress in a healthy population
title_full_unstemmed	Effect of the consumption of chocolate enriched with tryptophan and resveratrol on biochemical markers and oxidative stress in a healthy population
title_sort	effect of the consumption of chocolate enriched with tryptophan and resveratrol on biochemical markers and oxidative stress in a healthy population
publisher	Universidad de Antioquia
publishDate	2019
url	https://doaj.org/article/a1d689ceaf1f4a2b8106aa9521056735
work_keys_str_mv	AT jennyferflorezmendez effectoftheconsumptionofchocolateenrichedwithtryptophanandresveratrolonbiochemicalmarkersandoxidativestressinahealthypopulation AT jorgeyezidflorez effectoftheconsumptionofchocolateenrichedwithtryptophanandresveratrolonbiochemicalmarkersandoxidativestressinahealthypopulation AT elevinaperez effectoftheconsumptionofchocolateenrichedwithtryptophanandresveratrolonbiochemicalmarkersandoxidativestressinahealthypopulation AT marylares effectoftheconsumptionofchocolateenrichedwithtryptophanandresveratrolonbiochemicalmarkersandoxidativestressinahealthypopulation
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Effect of the consumption of chocolate enriched with tryptophan and resveratrol on biochemical markers and oxidative stress in a healthy population

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