Microglia control vascular architecture via a TGFβ1 dependent paracrine mechanism linked to tissue mechanics

During development and pathologies of the central nervous system, blood vessels are closely connected with the innate immune cells, microglia. Here, the authors report that microglia adjust their angiogenic program to shape blood vessels and may depend on tissue stiffness.

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Tejasvi Dudiki, Julia Meller, Gautam Mahajan, Huan Liu, Irina Zhevlakova, Samantha Stefl, Conner Witherow, Eugene Podrez, Chandrasekhar R. Kothapalli, Tatiana V. Byzova
Format: article
Langue:EN
Publié: Nature Portfolio 2020
Sujets:
Q
Accès en ligne:https://doaj.org/article/a21212a9194d4adfb582ac1eb647f6fd
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!