A quasi-integral controller for adaptation of genetic modules to variable ribosome demand
Competition for shared cellular resources often renders genetic circuits poorly predictable. Here the authors design a biomolecular quasi-integral controller that allows gene expression to adapt to variable demand in translation resources.
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Main Authors: | Hsin-Ho Huang, Yili Qian, Domitilla Del Vecchio |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2018
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Subjects: | |
Online Access: | https://doaj.org/article/a21277718beb4c2d8c7c9d40cb7e1f5f |
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